Predicting a structure with ESMFold

Enter the protein sequence using one-letter amino acid codes, and click one of the Predict buttons. After a few moments, the protein structure will be downloaded.

ESM Metagenomic Atlas (also referred to as "ESM Metagenomic Structure Atlas" or "ESM Atlas") data is available under a CC BY 4.0 license for academic and commercial use. Copyright(c) Meta Platforms, Inc. All Rights Reserved. Use of the ESM Metagenomic Structure Atlas data is subject to the Meta Open Source Terms of Use and Privacy Policy.

If you make use of a structure predicted by ESMFold, please cite the following paper:

Language models of protein sequences at the scale of evolution enable accurate structure prediction.

Zeming Lin, Halil Akin, Roshan Rao, Brian Hie, Zhongkai Zhu, Wenting Lu, Nikita Smetanin, Robert Verkuil, Ori Kabeli, Yaniv Shmueli, Allan dos Santos Costa, Maryam Fazel - Zarandi, Tom Sercu, Sal Candido, Alexander Rives. bioRxiv 2022.07.20.500902.

https://doi.org/10.1101/2022.07.20.500902

Predicting a structure with AlphaFold

Enter one or more FASTA files, choose the AlphaFold model (monomer, multimer, etc.) and the database for multiple sequence alignment, and click Start prediction.

Predictions are performed using a choice of cloud machines with varying performances and costs, including powerful instances with A100 GPUs.

You can obtain computing credits there.

Any publication that discloses findings arising from using the AlphaFold service should cite the AlphaFold paper and, if applicable, the AlphaFold-Multimer paper.

https://doi.org/10.1038/s41586-021-03819-2