This app computes axes of symmetry in protein complexes. It handles cyclic, dihedral, and cubic symmetries. The computed axes are displayed and the RMSD to perfect symmetry is given.

Documentation

Please refer to the tutorial on Computing axes of symmetry of biological assemblies.

References

This extension is based on research by Guillaume Pagès et al. at Inria.

[1] Guillaume Pagès, Elvira Kinzina, Sergei Grudinin. Analytical symmetry detection in protein assemblies. I. Cyclic symmetries. Journal of Structural Biology, Volume 203, Issue 2, August 2018, Pages 142-148.

[2] Guillaume Pagès, Sergei Grudinin. Analytical symmetry detection in protein assemblies. II. Dihedral and cubic symmetries. Journal of Structural Biology, Volume 203, Issue 3, September 2018, Pages 185-194.

[3] Guillaume Pagès, Sergei Grudinin. AnAnaS: Software for Analytical Analysis of Symmetries in Protein Structures. In: Kihara, D. (eds) Protein Structure Prediction. Methods in Molecular Biology, vol 2165. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0708-4_14.